Take the time to speak to everyone before you go as now, there’s a few more reputation points to earn that may help with your conversation choices at the end. Upgrade ALL weapons and tweak your armour as required.

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Wrap up conversations with your crew and chosen love interest before the final mission (left). Spec skills strong against the Reapers (right) before you go.

Also feel free to reassign your points and bonus skill so they’re heavily against organic life forms (sabotage doesn’t have any effect, even though the Reapers are part synthetic). Weapon classes should also look at upgrading the Cryo ammo-enhancer for this mission as it can help reduce the enemy fire by all-out freezing them for a time.