Now that you have access to the Altar of Despair you can return to the Vileblood Queen’s Chambers and pick up the Queenly Flesh , if you didn’t earlier. Take this to the Altar of Despair and interact with it to revive Annalise, Queen of the Vilebloods.

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Take the Queenly Flesh to the Altar of Despair to revive Annalise, if she was killed.